Publications

EBV and the making of lupus

Key findings from clinical trials conducted as part of the endTB project, which aimed to improve treatment for the most difficult form of tuberculosis.

A major discovery against leprosy thanks to an anti-tuberculosis drug: Bedaquiline

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice.

Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice.

Intra-muscular mRNA vaccines are poor inducers of mucosal immunity

Intestinal Candida albicans overgrowth in IgA deficiency

Mycobiota control : the IgA connection.

The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites

O. Silvie’s team has identified a Plasmodium protein that is essential for the motility and infectivity of sporozoites, the mosquito-transmitted forms of the malaria-causing parasite. This protein, called CLAMP, could constitute a new vaccine target.

Plasmodium sporozoites require the protein B9 to invade hepatocytes

O. Silvie’s team has identified a Plasmodium protein that is essential for the infection of hepatocytes during malaria. This protein, called B9, could constitute a new vaccine target.

T-independent responses to polysaccharides in humans mobilize marginal zone B cells prediversified against gut bacterial antigens

A novel CIMI collaboration underlines the key role played by the immune/microbiota interface in the pre-education of the human antibody repertoire.

“Lower disease activity but higher risk of severe COVID- 19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α”