New Publication – Allon Weiner’s team 07 July 2022

New Publication – Allon Weiner’s team

Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage. Lachat J., Pascault A., Thibaut D., Le Borgne R., Verbavatz J.M., Weiner A. Nat Commun 13, 3781 (2022). Free PMC Article.

« Malaria, asplenia : a story of sensing, swelling, sickling & pitting »

« Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses »

The effectiveness of a vaccine against #HIV

Dr Behazine Combadière, a lead investigator at the Centre for Immunology and Infectious Diseases @INSERM is working on predicting the effectiveness of a vaccine against #HIV which is concurrently advancing the #CovidVaccine development research.

Vaccine responses against SARS-CoV-2 variants examined in people with lupus

The majority of people with systemic lupus erythematosus (SLE) who respond to messenger (m)RNA COVID-19 vaccines also generate an antibody response against emerging SARS-CoV-2 variants, albeit with reduced neutralizing activity against variants bearing the E484K mutation, researchers report.

A personalized precision medicine approach is needed to treat Covid-19 as more than one type of “Cytokine storm” is induced by SARS-CoV-2

The severe form of Covid-19 is known to be associated with the excessive elevation of many cytokines, a condition termed “cytokine storm”. Therapy with biological agents intended to block these cytokines, for example anti-interleukin-6 or anti-interleukin-1 antibodies, was already tried, albeit with a limited success.