Intestinal Candida albicans overgrowth in IgA deficiency
Mycobiota control : the IgA connection.
The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites
O. Silvie’s team has identified a Plasmodium protein that is essential for the motility and infectivity of sporozoites, the mosquito-transmitted forms of the malaria-causing parasite. This protein, called CLAMP, could constitute a new vaccine target.
Plasmodium sporozoites require the protein B9 to invade hepatocytes
O. Silvie’s team has identified a Plasmodium protein that is essential for the infection of hepatocytes during malaria. This protein, called B9, could constitute a new vaccine target.
T-independent responses to polysaccharides in humans mobilize marginal zone B cells prediversified against gut bacterial antigens
A novel CIMI collaboration underlines the key role played by the immune/microbiota interface in the pre-education of the human antibody repertoire.
Team’s FRM 2022 – G Gorochov
Guy Gorochov’s team has been awarded the Equipe FRM 2022 label for the project «Study and manipulation of host-microbiota mutualism regulated by immunoglobulin A»
“Exploring the microbiome to displace multi-drug resistant Enterobacteria from the gut”
« Identification of key components of proteostasis regulation for diagnosis and targeting of inflammatory diseases and cancer »
“Lower disease activity but higher risk of severe COVID- 19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α”
Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage
Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage.